The final episode of "The Apothecary Diaries" second season, Episode 48 "The Beginning," was broadcast on Friday, July 4th (Japan Time). Following the episode, it was announced that its sequel is now in production!
"The Apothecary Diaries" is a hugely popular mystery-solving entertainment series set in the imperial palace, following a young poison tester as she solves various difficult cases. The original light novel series (written by Natsu Hyuuga and illustrated by Touko Shino, published by Hero Bunko/Imagica Infos) has surpassed 38 million copies in circulation.
Sequel Confirmed! Super Teaser PV Released!
Season 2 began with fresh developments: Consort Gyokuyō's pregnancy, Xiaolan's new journey, and the arrival of foreign envoys. However, beneath the surface, the inner palace's past and dark secrets stirred. Before she knew it, Maomao found herself embroiled in a major incident that shook the nation - the rebellion of the Shi clan.
Jinshi confronted his origins, leading the imperial guard as the emperor's brother to suppress the Shi clan. The story concluded with episode 48, titled "The Beginning."
Immediately after the broadcast, the announcement of a "sequel in production" was made during the TV airing. Simultaneously, a super teaser PV was released online.
The super teaser PV opens with a scene of Jinshi receiving a paper from Luolan in a fortress. Accompanied by the words of Maomao and Jinshi, the video is filled with scenes and keywords hinting at the sequel. The phrase "The stage moves to a new land" is followed by expansive wheat fields... Please look forward to the new story that will unfold in the sequel!
Comments from Original Author Natsu Hyuuga and Voice Actors!
Comment from Original Author: Natsu Hyuuga
I am incredibly grateful that the series will continue. The original plan was to adapt four novels into the first and second seasons, but now we are moving beyond that.
I feel immense pressure to make the upcoming content even more captivating and engaging. I am carefully reviewing the story to ensure nothing is missing, and I am also working to provide the best possible support for the anime production team.
As we embark on this extended journey, I humbly ask for your continued support. Thank you for staying with us as the story unfolds further.
Comment from Maomao's Voice Actor: Aoi Yuki
I'm incredibly excited about the sequel! I felt so sad when we finished recording the second season, but this news definitely lifts my spirits.
I'm also happy that we can announce the sequel at this perfect moment, which will surely help dispel the sadness of seeing such an epic story come to an end.
Everyone involved in "The Apothecary Diaries," regardless of their role, has a deep love for the series. They put so much care into preparing it for delivery to your homes. While we might have to ask you to wait a little longer for the sequel, I've heard that there are plenty of exciting plans in store to keep your enthusiasm alive during the wait. We'd be thrilled if you could continue to show your support for the series!
Comment from Jinshi's Voice Actor: Takeo Otsuka
Thank you to everyone who watched all the way through to the final episode of Season 2!
And we have exciting news - a sequel has been confirmed! Congratulations and thank you all!
I'm thrilled that we'll be able to continue exploring the world of "The Apothecary Diaries" through animation and that I'll have the opportunity to keep voicing these characters.
It seems there will be various exciting events and content to look forward to before the sequel airs. I hope you'll continue to support us through all of these upcoming activities!
Once again, thank you for your continued support, and please stay tuned for more from "The Apothecary Diaries"!
"The Apothecary Diaries" Season 2 Original Soundtrack Set for Release on September 17th!
The original soundtrack for Season 2 of the TV anime "The Apothecary Diaries," featuring 62 background music tracks that colored the second season, is set to be released on Wednesday, September 17, 2025! Along with this announcement, the newly drawn jacket artwork has been unveiled.
The jacket design complements the first season's soundtrack, which featured Maomao, by showcasing Jinshi in an original illustration. Be sure to check it out!
About "The Apothecary Diaries" Season 2 Original Soundtrack
Release Date: September 17 (Japan Time)
Price: 4,180 yen (3,800 yen excluding tax)
Music by: Satoru kousaki, Kevin Penkin, Alisa Okehazama
Specifications: Anime original jacket artwork, 2-CD set
Included Bonuses: Booklet, Jacket illustration sticker
Number of tracks: 62
<Disc 1>
1. Kusuriya no Musume (The Apothecary's Daughter)
2. Hi
3. Housenka -Shoukei-
4. Oshaberi (Chatter)
5. Jou-chan no Tomodachi (The Young Lady's Friend)
6. Tenarai-jo (Writing Practice Place)
7. Mushi-zuki na Gejo (The Bug-Loving Maid)
8. Touzoku-kai (Reformed Thief)
9. Omoshiro-sou da (Seems Interesting)
10. Blonde Beauty
11. Complex Situation
12. Taishou (Caravan)
13. Katte na Okusoku (Arbitrary Speculation)
14. Tsunagaru Jouhou (Connected Information)
15. Dancing Spirit of the Moon
16. Luna Moth
17. Be Troubled
18. Kakushin (Core)
19. Head Lady-in-Waiting of the Crystal Pavilion
20. Whiteblossom
21. Furui Shinkou (Old Belief)
22. Sentaku no Byou (Temple of Choice)
23. Oubo no Ketsuzoku (The Empress's Blood Relatives)
24. Office Work
25. The Emperor's Mother
26. Orpiment Clothing
27. Atarashii Jijo (New Lady-in-Waiting)
28. Ghost Story
29. Thirteen Tales
30. Kita no Shinryou-jo (Northern Clinic)
31. Ka Zuigetsu
32. Hihatsu
33. Kore, Nan da? (What's This?)
34. I Have Something to Tell You
<Disc 2>
1. Sobakasu no Shoujo (Freckled Girl)
2. Sakago (Breech Birth)
3. Evening Concert
4. Yudono (Bathhouse)
5. Yudono no Yuurei (Bathhouse Ghost)
6. Kanzashi (Hairpin)
7. Koori-gashi (Ice Confection)
8. Oyaji (Old Man)
9. Derarenai Inner Palace (Inescapable Inner Palace)
10. An'yaku (Secret Maneuvering)
11. Higashi no Kitsune (Eastern Fox)
12. Sato no Kodomo-tachi (Village Children)
13. Kodomo-tachi no Mirai (Children's Future)
14. A Group of Foxes
15. Harvest Festival
16. Wish
17. Iboshimai (Half-Sisters)
18. Ketsuzoku no Shukumei (Fate of Blood Relatives)
19. Roku demo nai Gaki (Good-for-nothing Brat)
20. Madam
21. Houzuki (Chinese Lantern Plant)
22. Kakugo wo Kimeru Toki (Time to Make a Decision)
23. Yaraneba (Must Do It)
24. Yuumoa (Humor)
25. Powder Magazine
26. Secret Feelings
27. Nadare (Avalanche)
28. Inochi no Tomoshibi (Light of Life)
Song by: Rimu Miyake
Lyrics by: Mashiro Uchida
About "The Apothecary Diaries" Season 2
Synopsis
When the emperor's high-ranking consort, Gyokuyō, discovered she was pregnant, Maomao returned to her role as the Jade Pavilion's poison-tester. She remained vigilant to ensure no further incidents would target the consort and the emperor's son.
A new consort, Loulan, whose father was an influential minister from the previous emperor's reign, entered the palace. An unprecedented unsolved case emerged, where the emperor's life was threatened, and the suspect, Suirei, disappeared.
As the unsettling atmosphere persisted, foreign traders and ambassadors with unreasonable demands also arrived. More dark clouds were beginning to gather over the court.
The new challenges facing Maomao and Jinshi will eventually escalate into a major incident involving the entire country----
Cast
Maomao: Aoi Yuki
Jinshi: Takeo Otsuka
Gaoshun: Katsuyuki Konishi
Consort Gyokuyō: Atsumi Tanezaki
Consort Lihua: Yui Ishikawa
Consort Lishu: Hina Kino
Xiaolan: Misaki Kuno
Shisui: Asami Seto
Ayla: Lynn
Aylin: Yumi Hara
Lahan: Toshiyuki Toyonaga
Shenmei: Rika Fukami
Narrator: Sumi Shimamoto
©Hyuganatsu, Imagica Infos/“The Apothecary Diaries”Project
※Some parts of this text have been translated using machine translation
